Adaptive immune response essay

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Smad proteins in the resting state realize passive nucleo cytoplasmic shuttling, that is controlled by two opposing signals: the nuclear localization signal NLS in the MH1 domain and the nuclear export signal NES in the MH2 domain. Then they interact with DNA binding proteins or directly regulate transcriptional activity, either as monomers or in association with Smad4 Carreira et al. In the nucleus they can regulate transcription of target genes by directly binding via their MH1 domain to specific DNA sequences depends on the formation of Smad complex with other DNA-binding proteins. Smad complex binds the promotor regions of several BMP-responsive genes. Monoclonal antibody therapy is a type of immunotherapy that recognizes and attaches to cells or proteins.
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42.2: Adaptive Immune Response

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Disorders of the Immune System | NIH: National Institute of Allergy and Infectious Diseases

In: Science. If left untreated it can lead to AIDS. The human body cannot get rid of HIV. That means that once you have HIV, you have it for life. Most children who are born to mothers who have HIV do not become infected with this virus. In the case that they do become infected, their response to treatment varies depending upon the timing and potentially the route of their infection. This transmission may occur if there is damage to the placenta and blood from the mother contact the fetus.
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Innate and Adaptive Immune Responses on First and Subsequent Exposure to a Pathogen

Describe and compare the external and internal innate defenses that protect us from microbes and other substances that could invade and harm the body. The human body contains two lines of defence. External barriers and internal defenses both are Innate defenses fully ready to respond. However recent evidence suggests that mere presence of putative periodontal pathogens is not sufficient for initiation of disease process 2.
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Adaptive and Innate Immunity A pathogen is a disease causing agent which includes a vast amount of microorganisms: viruses, bacteria, fungi, protozoa, worms, and parasites. Antigens are agents which stimulate an immune response. Most antigens are pathogens which stimulate a strong immune response. The purpose of the innate immunity system is to keep away all pathogens.
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